the next year, she released a study showing that HPV-positive and HPV-negative oropharyngeal cancers had completely different risk profiles.more at
People with HPV-positive cancer tended to have had many oral-sex partners, but there was no statistical association with tobacco smoking or drinking;
those with HPV-negative cancers were heavy drinkers and cigarette smokers but there was no association with sexual activity.
“These were two completely different diseases,” says Gillison. “They might superficially look similar — a patient comes in with a neck mass and their throat hurts — but I realized what drove the pathogenesis was completely different in the two cases.”